Invitrogen™ UGT1A6 Polyclonal Antibody

Catalog No.	Quantity
PIPA5143878	100 μg

Catalog No. PIPA5143878 Supplier Invitrogen™ Supplier No. PA5143878

Description

Rabbit Polyclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human HEK293 whole cell. ICC/IF: U2OS cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

UGT1A6 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.

Specifications

• Antigen: UGT1A6
• Applications: ELISA, Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 500 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene: UGT1A6
• Gene Accession No.: P19224
• Gene Alias: A1; GNT1; HLUGP; HLUGP1; MGC29860; Phenol UDP-glucuronosyltransferase; phenol-metabolizing UDP-glucuronosyltransferase; P-nitrophenol specific; P-nitrophenol-specific UDPGT; UDP glucuronosyltransferase 1 family, polypeptide A6; UDP glucuronosyltransferase 1 family, polypeptide A6A; UDP glucuronosyltransferase 1A6; UDP glucuronosyltransferase family 1 member A6; UDP glycosyltransferase 1 family polypeptide A4; UDP glycosyltransferase 1 family, polypeptide A6; UDP-glucuronosyltransferase; UDP-glucuronosyltransferase 1 family polypeptide A6s; UDP-glucuronosyltransferase 1-6; UDP-glucuronosyltransferase 1A6; UDP-glucuronosyltransferase 1-F; Udpgt; UDPGT 1-6; UGP1A1; UGT1; UGT1*6; UGT1.6; UGT1-06; Ugt1a6; Ugt1a6a; UGT1A6S; UGT1A7; UGT1F; UGT-1F
• Gene Symbols: UGT1A6
• Host Species: Rabbit
• Immunogen: E.coli-derived human UGT1A6 recombinant protein (Position: D27-S251).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 54578
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG