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Invitrogen™ UGT1A6 Polyclonal Antibody
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Catalog No. PIPA562911
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100 μL
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PIPA562911 100 μL
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Catalog No. PIPA562911 Supplier Invitrogen™ Supplier No. PA562911
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: WLSMKDIVEV LSDRGHEIVV VVPEVNLLLK ESKYYTRKIY PVPYDQEELK NRYQSFGNNH FAERSFLTAP QTEYRNNMIV IGLY Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 73%.

UGT1A6 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UGT1A6
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration Lot-Specific
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene UGT1A6
Gene Accession No. P19224
Gene Alias A1; GNT1; HLUGP; HLUGP1; MGC29860; Phenol UDP-glucuronosyltransferase; phenol-metabolizing UDP-glucuronosyltransferase; P-nitrophenol specific; P-nitrophenol-specific UDPGT; UDP glucuronosyltransferase 1 family, polypeptide A6; UDP glucuronosyltransferase 1 family, polypeptide A6A; UDP glucuronosyltransferase 1A6; UDP glucuronosyltransferase family 1 member A6; UDP glycosyltransferase 1 family polypeptide A4; UDP glycosyltransferase 1 family, polypeptide A6; UDP-glucuronosyltransferase; UDP-glucuronosyltransferase 1 family polypeptide A6s; UDP-glucuronosyltransferase 1-6; UDP-glucuronosyltransferase 1A6; UDP-glucuronosyltransferase 1-F; Udpgt; UDPGT 1-6; UGP1A1; UGT1; UGT1*6; UGT1.6; UGT1-06; Ugt1a6; Ugt1a6a; UGT1A6S; UGT1A7; UGT1F; UGT-1F
Gene Symbols UGT1A6
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human UGT1A6. Recombinant protein control fragment (Product #RP-103807).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54578
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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