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Invitrogen™ UGT1A6 Polyclonal Antibody
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Catalog No. PIPA522319
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100 μL
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PIPA522319 100 μL
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Catalog No. PIPA522319 Supplier Invitrogen™ Supplier No. PA522319
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, HeLa, HepG2, H1299, mouse liver. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

UGT1A6 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UGT1A6
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.56 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene UGT1A6
Gene Accession No. P19224, Q64435
Gene Alias A1; GNT1; HLUGP; HLUGP1; MGC29860; Phenol UDP-glucuronosyltransferase; phenol-metabolizing UDP-glucuronosyltransferase; P-nitrophenol specific; P-nitrophenol-specific UDPGT; UDP glucuronosyltransferase 1 family, polypeptide A6; UDP glucuronosyltransferase 1 family, polypeptide A6A; UDP glucuronosyltransferase 1A6; UDP glucuronosyltransferase family 1 member A6; UDP glycosyltransferase 1 family polypeptide A4; UDP glycosyltransferase 1 family, polypeptide A6; UDP-glucuronosyltransferase; UDP-glucuronosyltransferase 1 family polypeptide A6s; UDP-glucuronosyltransferase 1-6; UDP-glucuronosyltransferase 1A6; UDP-glucuronosyltransferase 1-F; Udpgt; UDPGT 1-6; UGP1A1; UGT1; UGT1*6; UGT1.6; UGT1-06; Ugt1a6; Ugt1a6a; UGT1A6S; UGT1A7; UGT1F; UGT-1F
Gene Symbols UGT1A6, Ugt1a6a
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human UGT1A6. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54578, 94284
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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