Invitrogen™ UGT1A9 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120467

Catalog No. PIPA5120467

Description

Positive test controls include: A-549, HT-29, MCF7, HeLa, Mouse liver. The target is usually found in the following locations: Endoplasmic reticulum membrane, Microsome, Single-pass membrane protein. Immunogen sequence: GKLLVVPMDG SHWFTMRSVV EKLILRGHEV VVVMPEVSWQ LGRSLNCTVK TYSTSYTLED LDREFKAFAH AQWKAQVRSI YSLLMGSYND IFDLFFSNCR SLFKDKKLVE YLKESSFDAV FLDPFDNCGL IVAKYFSLPS VVFARGILCH YLEEGAQCPA PLSYVPRILL GFSDAMTFKE RVRNHIMHLE EHLLCHRFFK NALEIASEIL QTPVTEYDLY SHTSI.

UGT1A9 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. UGT1A9 is active on phenols.This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Specifications

• Antigen: UGT1A9
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UGT1A9
• Gene Alias: GNT1; HLUGP4; LUGP4; mUGTBr/P; SHEUGT1A07; UDP glucuronosyltransferase 1 family, polypeptide A9; UDP glucuronosyltransferase family 1 member A9; UDP glycosyltransferase 1 family polypeptide A10; UDP glycosyltransferase 1 family polypeptide A11; UDP glycosyltransferase 1 family polypeptide A12; UDP glycosyltransferase 1 family, polypeptide A10; UDP glycosyltransferase 1 family, polypeptide A9; UDP-glucuronosyltransferase; UDP-glucuronosyltransferase 1 family polypeptide A9s; UDP-glucuronosyltransferase 1-7; UDP-glucuronosyltransferase 1-9; UDP-glucuronosyltransferase 1A9; UDP-glucuronosyltransferase 1-I; UDPGT; UDPGT 1-9; UGT1; UGT1.9; UGT1-09; UGT1-9; Ugt1a10; Ugt1a11; Ugt1a12; UGT1A9; UGT1A9S; UGT1AI; UGT1I; UGT-1I; UGTP4
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 394434, 396552, 54600
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.56 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O60656, Q62452
• Gene Symbols: UGT1A9
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-250 of human UGT1A9 (NP_066307.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG