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Invitrogen™ UGT2B4 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA592155
Description
Immunogen sequence: LHCKPAKPLP KEMEEFVQSS GENGVVVFSL GSMVSNTSEE RANVIASALA KIPQKVLWRF DGNKPDTLGL NTRLYKWIPQ NDLLGHPKTR AFITHGGANG IYEAIYHGIP MVGVPLFADQ PDNIAHMKAK GAAVSLDFHT MSSTDLLNAL KTVINDPLYK ENAMKLSRIH HDQPVKPLDR AVFWIEFVMR HKGAKHLRVA A; Positive Samples: 22Rv1, B cells, HT-1080, Mouse liver, Mouse brain, Mouse kidney, Rat kidney; Cellular Location: Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein.
UGT2B4 belongs to the UDP-glycosyltransferase family. UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
Specifications
UGT2B4 | |
Polyclonal | |
Unconjugated | |
UGT2B4 | |
HLUG25; hyodeoxycholic acid; hyodeoxycholic acid-specific UDPGT; UDP glucuronosyltransferase 2 family, polypeptide B15; UDP glucuronosyltransferase 2 family, polypeptide B36; UDP glucuronosyltransferase 2 family, polypeptide B4; UDP glucuronosyltransferase family 2 member B4; UDP glycosyltransferase 2 family, polypeptide B4; UDP-glucuronosyltransferase 2B12; UDP-glucuronosyltransferase 2B15; UDP-glucuronosyltransferase 2B36; UDP-glucuronosyltransferase 2B4; UDP-glucuronyltransferase, family 2, beta-4; UDPGT 2B12; UDPGT 2B15; UDPGT 2B36; UDPGT 2B4; UDPGT2B4; UDPGTH1; UDPGTh-1; UGT2B11; Ugt2b12; Ugt2b15; Ugt2b36; UGT2B4 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
7363 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot | |
1.84 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P06133 | |
UGT2B4 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human UGT2B4 (NP_0669622). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
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