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Invitrogen™ UGT2B4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA592155

Catalog No. PIPA592155


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Description

Description

Immunogen sequence: LHCKPAKPLP KEMEEFVQSS GENGVVVFSL GSMVSNTSEE RANVIASALA KIPQKVLWRF DGNKPDTLGL NTRLYKWIPQ NDLLGHPKTR AFITHGGANG IYEAIYHGIP MVGVPLFADQ PDNIAHMKAK GAAVSLDFHT MSSTDLLNAL KTVINDPLYK ENAMKLSRIH HDQPVKPLDR AVFWIEFVMR HKGAKHLRVA A; Positive Samples: 22Rv1, B cells, HT-1080, Mouse liver, Mouse brain, Mouse kidney, Rat kidney; Cellular Location: Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein.

UGT2B4 belongs to the UDP-glycosyltransferase family. UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

UGT2B4
Polyclonal
Unconjugated
UGT2B4
HLUG25; hyodeoxycholic acid; hyodeoxycholic acid-specific UDPGT; UDP glucuronosyltransferase 2 family, polypeptide B15; UDP glucuronosyltransferase 2 family, polypeptide B36; UDP glucuronosyltransferase 2 family, polypeptide B4; UDP glucuronosyltransferase family 2 member B4; UDP glycosyltransferase 2 family, polypeptide B4; UDP-glucuronosyltransferase 2B12; UDP-glucuronosyltransferase 2B15; UDP-glucuronosyltransferase 2B36; UDP-glucuronosyltransferase 2B4; UDP-glucuronyltransferase, family 2, beta-4; UDPGT 2B12; UDPGT 2B15; UDPGT 2B36; UDPGT 2B4; UDPGT2B4; UDPGTH1; UDPGTh-1; UGT2B11; Ugt2b12; Ugt2b15; Ugt2b36; UGT2B4
Rabbit
Affinity Chromatography
RUO
7363
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot
1.84 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P06133
UGT2B4
Recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human UGT2B4 (NP_0669622).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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