Invitrogen™ UGT8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103177

Catalog No. PIPA5103177

Description

Antibody detects endogenous levels of total UGT8.

UGT8 (UDP-galactose-ceramide galactosyltransferase, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase) is a 541 amino acid, single pass membrane protein of the UDP-glycosyltransferase family. UGT8 is believed to be primarily involved with the metabolism of sphingolipids and galactosylceramide biosynthesis. UGT8 is one of six genes whose elevated expression has been correlated with a significantly increased the risk of lung metastases in breast cancer patients. As such, UGT8 may be a significant index of tumor aggressiveness and a potential marker for the prognostic evaluation of lung metastases in breast cancer. UGT8 is ubiquitously expressed with highest levels found in central and peripheral nervous systems and is up-regulated in breast cancers.

Specifications

• Antigen: UGT8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ugt8
• Gene Alias: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase; AI850488; AW455908; ceramide UDP-galactosyltransferase; Cerebroside synthase; Cgt; mCerGT; UDP galactosyltransferase 8; UDP galactosyltransferase 8A; UDP glycosyltransferase 8; UDP-galactose ceramide galactosyltransferase; UDP-galactose-ceramide galactosyltransferase; UDP-galactose-ceramide galactosyltransferase 8; UDP-galactose-ceramide galactosyltransferase 8A; UDP-glucuronosyltransferase 8; Ugt4; UGT8; Ugt8a; uridine diphosphate glycosyltransferase 8
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 50555, 7368
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q09426, Q16880
• Gene Symbols: Ugt8
• Immunogen: A synthesized peptide derived from human UGT8(Accession Q16880), corresponding to amino acid residues A305-F355.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov