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Invitrogen™ UGT8 Polyclonal Antibody
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Catalog No. PIPA537282
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100 μL
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PIPA537282 100 μL
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Catalog No. PIPA537282 Supplier Invitrogen™ Supplier No. PA537282
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 61 kDa. Purity is >95% by SDS-PAGE.

UGT8 (UDP-galactose-ceramide galactosyltransferase, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase) is a 541 amino acid, single pass membrane protein of the UDP-glycosyltransferase family. UGT8 is believed to be primarily involved with the metabolism of sphingolipids and galactosylceramide biosynthesis. UGT8 is one of six genes whose elevated expression has been correlated with a significantly increased the risk of lung metastases in breast cancer patients. As such, UGT8 may be a significant index of tumor aggressiveness and a potential marker for the prognostic evaluation of lung metastases in breast cancer. UGT8 is ubiquitously expressed with highest levels found in central and peripheral nervous systems and is up-regulated in breast cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UGT8
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Ugt8
Gene Accession No. Q09426, Q16880, Q64676
Gene Alias 2-hydroxyacylsphingosine 1-beta-galactosyltransferase; AI850488; AW455908; ceramide UDP-galactosyltransferase; Cerebroside synthase; Cgt; mCerGT; UDP galactosyltransferase 8; UDP galactosyltransferase 8A; UDP glycosyltransferase 8; UDP-galactose ceramide galactosyltransferase; UDP-galactose-ceramide galactosyltransferase; UDP-galactose-ceramide galactosyltransferase 8; UDP-galactose-ceramide galactosyltransferase 8A; UDP-glucuronosyltransferase 8; Ugt4; UGT8; Ugt8a; uridine diphosphate glycosyltransferase 8
Gene Symbols Ugt8, Ugt8a
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues in human UGT8.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22239, 50555, 7368
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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