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Invitrogen™ UGT8 Polyclonal Antibody
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Catalog No. PIPA5111606
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100 μL
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PIPA5111606 100 μL
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LGVSFLVLPK YERIMQKYNL LPEKSMYDLV HGSSLWMLCT DVALEFPRPT LPNVVYVGGI LTKPASPLPE DLQRWVNGAN EHGFVLVSFG AGVKYLSEDI ANKLAGA Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 96%.

UGT8 (UDP-galactose-ceramide galactosyltransferase, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase) is a 541 amino acid, single pass membrane protein of the UDP-glycosyltransferase family. UGT8 is believed to be primarily involved with the metabolism of sphingolipids and galactosylceramide biosynthesis. UGT8 is one of six genes whose elevated expression has been correlated with a significantly increased the risk of lung metastases in breast cancer patients. As such, UGT8 may be a significant index of tumor aggressiveness and a potential marker for the prognostic evaluation of lung metastases in breast cancer. UGT8 is ubiquitously expressed with highest levels found in central and peripheral nervous systems and is up-regulated in breast cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UGT8
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Ugt8
Gene Accession No. Q16880
Gene Alias 2-hydroxyacylsphingosine 1-beta-galactosyltransferase; AI850488; AW455908; ceramide UDP-galactosyltransferase; Cerebroside synthase; Cgt; mCerGT; UDP galactosyltransferase 8; UDP galactosyltransferase 8A; UDP glycosyltransferase 8; UDP-galactose ceramide galactosyltransferase; UDP-galactose-ceramide galactosyltransferase; UDP-galactose-ceramide galactosyltransferase 8; UDP-galactose-ceramide galactosyltransferase 8A; UDP-glucuronosyltransferase 8; Ugt4; UGT8; Ugt8a; uridine diphosphate glycosyltransferase 8
Gene Symbols Ugt8
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human UGT8. Recombinant protein control fragment (Product #RP-107455).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7368
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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