Invitrogen™ UGT8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5118340

Catalog No. PIPA5118340

Description

UGT8 Polyclonal Antibody for Western Blot, IP

UGT8 (UDP-galactose-ceramide galactosyltransferase, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase) is a 541 amino acid, single pass membrane protein of the UDP-glycosyltransferase family. UGT8 is believed to be primarily involved with the metabolism of sphingolipids and galactosylceramide biosynthesis. UGT8 is one of six genes whose elevated expression has been correlated with a significantly increased the risk of lung metastases in breast cancer patients. As such, UGT8 may be a significant index of tumor aggressiveness and a potential marker for the prognostic evaluation of lung metastases in breast cancer. UGT8 is ubiquitously expressed with highest levels found in central and peripheral nervous systems and is up-regulated in breast cancers.

Specifications

• Antigen: UGT8
• Classification: Polyclonal
• Formulation: PBS with 0.03% ProClin 300; pH 7
• Gene Accession No.: Q16880
• Gene Symbols: Ugt8
• Immunogen: E. coli-derived Human UGT8 fragment.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Gene: Ugt8
• Gene Alias: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase; AI850488; AW455908; ceramide UDP-galactosyltransferase; Cerebroside synthase; Cgt; mCerGT; UDP galactosyltransferase 8; UDP galactosyltransferase 8A; UDP glycosyltransferase 8; UDP-galactose ceramide galactosyltransferase; UDP-galactose-ceramide galactosyltransferase; UDP-galactose-ceramide galactosyltransferase 8; UDP-galactose-ceramide galactosyltransferase 8A; UDP-glucuronosyltransferase 8; Ugt4; UGT8; Ugt8a; uridine diphosphate glycosyltransferase 8
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 7368
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid