UGT8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 179821AP
This antibody specifically recognizes the endogenous UGT8.UGT8 (UDP-galactose-ceramide galactosyltransferase, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase) is a 541 amino acid, single pass membrane protein of the UDP-glycosyltransferase family. UGT8 is believed to be primarily involved with the metabolism of sphingolipids and galactosylceramide biosynthesis. UGT8 is one of six genes whose elevated expression has been correlated with a significantly increased the risk of lung metastases in breast cancer patients. As such, UGT8 may be a significant index of tumor aggressiveness and a potential marker for the prognostic evaluation of lung metastases in breast cancer. UGT8 is ubiquitously expressed with highest levels found in central and peripheral nervous systems and is up-regulated in breast cancers.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|Q09426, Q16880, Q64676|
|ceramide galactosyltransferase, Cerebroside synthase, CGT, UDP glycosyltransferase 8, UGT4, UGT8|
|22239, 50555, 7368|
|Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|UGT8 Fusion Protein Ag12393|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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