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Invitrogen™ UHRF1 Polyclonal Antibody
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Catalog No. PIPA537440
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PIPA537440 100 μL
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Catalog No. PIPA537440 Supplier Invitrogen™ Supplier No. PA537440
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Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 90 and 110 kDa. Purity is >95% by SDS-PAGE.

This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UHRF1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene UHRF1
Gene Accession No. Q8VDF2, Q96T88
Gene Alias Ac2-121; AL022808; E3 ubiquitin-protein ligase UHRF1; fb97f09; FLJ21925; hNP95; Hnp95 Huhrf1; hUHRF1; HuNp95; ICBP90; inverted CCAAT box-binding protein of 90 kDa; Liver regeneration-related protein LRRG126; MGC138707; mUhrf1; Np95; nuclear phosphoprotein 95; nuclear protein; nuclear protein 95; Nuclear zinc finger protein Np95; RING finger protein 106; RING-type E3 ubiquitin transferase UHRF1; RNF106; TDRD22; transcription factor ICBP90; ub; ubiquitin like with PHD and ring finger domains 1; ubiquitin-like PHD and RING finger domain-containing protein 1; ubiquitin-like with PHD and ring finger domains 1; ubiquitin-like, containing PHD and RING finger domains, 1; ubiquitin-like-containing PHD and RING finger domains protein 1; Uhrf1; unm b1115; unm_b1115; wu:fb97f09; zgc:63539
Gene Symbols UHRF1
Host Species Rabbit
Immunogen Recombinant full length human UHRF1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18140, 29128
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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