UHRF2 Monoclonal Antibody (OTI4E10), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA810202

Catalog No. 50-168-3253

Description

This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.

Specifications

• Antigen: UHRF2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q96PU4
• Gene Symbols: UHRF2
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-288 of human UHRF2 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI4E10
• Conjugate: Unconjugated
• Gene: UHRF2
• Gene Alias: NIRF, RNF107, TDRD23, URF2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 115426
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid