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Invitrogen™ UHRF2 Polyclonal Antibody
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Catalog No. PIPA5110547
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100 μL
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PIPA5110547 100 μL
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Catalog No. PIPA5110547 Supplier Invitrogen™ Supplier No. PA5110547
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DSSLPSTSKQ NDAQVKPSSH NPPKVKKTAR GGSSSQPSTS ARTCLIDPGF GLYKVNELVD ARDVGLGAWF EAHIHSVTRA SDGHSRGKTP LKNGSSYKRT NGNVNHNSKE NTNKLDNVPS TSNSDSVAAD EDVIYHIEYD EYPESGILEM NVKDLRPRAR TILKWNELNV GDVVMVNYNV ENPGKRGFWY DAEITTLKTI SRTKKEVRVK VFLGGSEGTL NDCRVMSVDE IFKIEKPGAH PISFADGKFL RKNDPECDLC GGDPDKTCHM CSCHKCGEKR DPNM.

This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UHRF2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.71 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene UHRF2
Gene Accession No. Q7TMI3
Gene Alias 2310065A22Rik; AI426270; AW214556; D130071B19Rik; E3 ubiquitin-protein ligase UHRF2; Nirf; np95/ICBP90-like RING finger protein; Np95-like ring finger protein; Nuclear protein 97; nuclear zinc finger protein Np97; RING finger protein 107; RING-type E3 ubiquitin transferase UHRF2; RNF107; RP11-472F14.2; TDRD23; ubiquitin like with PHD and ring finger domains 2; ubiquitin-like PHD and RING finger domain-containing protein 2; ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase; ubiquitin-like, containing PHD and RING finger domains 2; ubiquitin-like, containing PHD and RING finger domains, 2; ubiquitin-like-containing PHD and RING finger domains protein 2; UHRF2; URF2
Gene Symbols UHRF2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 76-359 of mouse Uhrf2 (NP_659122.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 109113, 309331
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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