Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Unclassified Organic Compounds
  6. 290010

UK 370106, Tocris Bioscience™

Click to view available options
Quantity:
10 mg
This item is not returnable. View return policy
230961-21-4
C35H44N2O5
572.746
NSMABJUGSNPHMN-BHYWQNONSA-N
r-3-s-1-s-2-methoxy-1-phenylethylamino-3,3-dimethyl-1-oxobutan-2-ylcarbamoyl-6-2-methylbiphenyl-4-yl hexanoic acid, 3r-3-1s-1-1s-2-methoxy-1-phenylethyl carbamoyl-2,2-dimethylpropyl carbamoyl-6-2-methyl-1,1'-biphenyl-4-yl hexanoic acid, ?r-?-1s-1-1s-2-methoxy-1-phenylethyl amino carbonyl-2,2-dimethylpropyl amino carbonyl-2-methyl-1,1'-biphenyl-4-hexanoic acid, betar-beta-1s-1-1s-2-methoxy-1-phenylethyl amino carbonyl-2,2-dimethylpropyl amino carbonyl-2-methyl-1,1'-biphenyl-4-hexanoic acid, r-3-s-1-s-2-methoxy-1-phenylethyl amino-3,3-dimethyl-1-oxobutan-2-yl carbamoyl-6-2-methyl-1,1'-biphenyl-4-yl hexanoic acid, r-3-s-1-s-2-methoxy-1-phenylethylamino-3,3-dimethyl-1-oxobutan-2-ylcarbamoyl-6-2-methyl biphenyl-4-yl hexanoic acid, r-3-s-1-s-2-methoxy-1-phenyl-ethylcarbamoyl-2,2-dimethyl-propylcarbamoyl-6-2-methyl-biphenyl-4-yl-hexanoic acid
9808181
(3R)-3-[[(2S)-1-[[(1S)-2-methoxy-1-phenylethyl]amino]-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl]-6-(3-methyl-4-phenylphenyl)hexanoic acid
CC1=C(C=CC(=C1)CCCC(CC(=O)O)C(=O)NC(C(=O)NC(COC)C2=CC=CC=C2)C(C)(C)C)C3=CC=CC=C3
This item is not returnable. View return policy
230961-21-4
C35H44N2O5
572.746
NSMABJUGSNPHMN-BHYWQNONSA-N
r-3-s-1-s-2-methoxy-1-phenylethylamino-3,3-dimethyl-1-oxobutan-2-ylcarbamoyl-6-2-methylbiphenyl-4-yl hexanoic acid, 3r-3-1s-1-1s-2-methoxy-1-phenylethyl carbamoyl-2,2-dimethylpropyl carbamoyl-6-2-methyl-1,1'-biphenyl-4-yl hexanoic acid, ?r-?-1s-1-1s-2-methoxy-1-phenylethyl amino carbonyl-2,2-dimethylpropyl amino carbonyl-2-methyl-1,1'-biphenyl-4-hexanoic acid, betar-beta-1s-1-1s-2-methoxy-1-phenylethyl amino carbonyl-2,2-dimethylpropyl amino carbonyl-2-methyl-1,1'-biphenyl-4-hexanoic acid, r-3-s-1-s-2-methoxy-1-phenylethyl amino-3,3-dimethyl-1-oxobutan-2-yl carbamoyl-6-2-methyl-1,1'-biphenyl-4-yl hexanoic acid, r-3-s-1-s-2-methoxy-1-phenylethylamino-3,3-dimethyl-1-oxobutan-2-ylcarbamoyl-6-2-methyl biphenyl-4-yl hexanoic acid, r-3-s-1-s-2-methoxy-1-phenyl-ethylcarbamoyl-2,2-dimethyl-propylcarbamoyl-6-2-methyl-biphenyl-4-yl-hexanoic acid
9808181
(3R)-3-[[(2S)-1-[[(1S)-2-methoxy-1-phenylethyl]amino]-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl]-6-(3-methyl-4-phenylphenyl)hexanoic acid
CC1=C(C=CC(=C1)CCCC(CC(=O)O)C(=O)NC(C(=O)NC(COC)C2=CC=CC=C2)C(C)(C)C)C3=CC=CC=C3

Description

Highly selective MMP-3 and MMP-12 inhibitor

Highly selective MMP-3 and MMP-12 inhibitor (IC50 values are 0.023, 0.042, 1.75, 2.3, 5.8, 30.4, 34.2 and 66.9 μM at MMP 3, 12, 8, 13, 7, 9, 2 and 14 respectively.) Inhibits fibronectin cleavage (IC50 = 320 nM) and has little effect on keratinocyte migration in vitro. Substantially inhibits MMP-3 in an ex vivo model of chronic dermal ulcers.
Quantity 10 mg
Formula Weight 572.73
Percent Purity >95%
Chemical Name or Material UK 370106

Safety and Handling

Recommended Storage : Store at +4°C

Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit