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Invitrogen™ ULK2 Polyclonal Antibody
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Catalog No. PIPA590315
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100 μL
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PIPA590315 100 μL
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Catalog No. PIPA590315 Supplier Invitrogen™ Supplier No. PA590315
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MEVVGDFEYS KRDLVGHGAF AVVFRGRHRQ KTDWEVAIKS INKKNLSKSQ ILLGKEIKIL KELQHENIVA LYDVQELPNS VFLVMEYCNG GDLADYLQAK; Positive Samples: PC-3; Cellular Location: Cytoplasmic vesicle membrane, Peripheral membrane protein.

ULK2, also known as ATG1B, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with its related protein ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. Like ULK1, ULK2 is also thought to be involved in early neuronal growth and differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ULK2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.03 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene ULK2
Gene Accession No. Q8IYT8
Gene Alias A830085I22Rik; ATG1B; AU015340; EC:2.7.11.1; KIAA0623; mKIAA0623; serine/threonine-protein kinase ULK2; Serine/threonine-protein kinase Unc51.2; ULK2; unc-51 like autophagy activating kinase 2; unc-51 like kinase 2; Unc51.2; unc-51-like kinase 2
Gene Symbols ULK2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ULK2 (NP_0011360821).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 303206, 9706
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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