Invitrogen™ ULK3 Monoclonal Antibody (1404CT148.89.25)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA537660

Catalog No. PIMA537660

Description

ULK3 Monoclonal Antibody for Western Blot, IHC (P)

ULK3 or unc-51-like kinase 3 is a member of the serine/threonine kinase family that is involved in the SHH signaling pathway as a positive regulator of GLI proteins. ULK3 enhances endogenous and over-expressed GLI transcriptional activity in cultured cells and alters its subcellular localization. Furthermore, ULK3 phosphorylates GLI proteins in vitro. ULK3 is widely expressed and its expression is higher in a number of tissues where SHH signaling is known to be active, again suggesting that ULK3 is involved in the SHH pathway as a positive regulator of GLI proteins.

Specifications

• Antigen: ULK3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: ULK3
• Gene Alias: 1200015E14Rik; DKFZP434C131; EC:2.7.11.1; FLJ90566; Serine/threonine-protein kinase ULK3; ULK3; unc-51 like kinase 3; unc-51-like kinase 3
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 25989, 691171, 71742
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 1404CT148.89.25
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: D3ZHP7, Q3U3Q1, Q6PHR2
• Gene Symbols: ULK3
• Immunogen: KLH conjugated synthetic peptide between 435-468 amino acids from the C-terminal region of human ULK3.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1 κ