Invitrogen™ UMPS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA557559

Catalog No. PIPA557559

Description

Immunogen sequence: GLKVTDAIVL LDREQGGKDK LQAHGIRLHS VCTLSKMLEI LEQQKKVDAE TVGRVKRFIQ ENVFVAANHN ASPLSIKEAP KELSFGARAE LPRIHPVA Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 85%.

This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Specifications

• Antigen: UMPS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UMPS
• Gene Alias: 1700095D23Rik; AA408257; AL033308; BB164745; mutant uridine monophosphate synthase; ODC; OK/SW-cl.21; OMPdecase; OPRT; OPRTase; orotate phosphoribosyl transferase and orotidine-5'-decarboxylase; orotate phosphoribosyltransferase; Orotidine 5'-phosphate decarboxylase; UMP synthase; UMPS; Uridine 5'-monophosphate synthase; uridine 5-monophosphate synthase; uridine 5'-monophosphate synthase-like protein; uridine monophophate synthase; uridine monophosphate synthase; uridine monophosphate synthetase; uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase); uridine monophosphate synthetase [orotate phosphoribosyl transferase and orotidine-5'-decarboxylase]
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22247, 288051, 7372
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P11172, P13439
• Gene Symbols: UMPS
• Immunogen: Recombinant protein corresponding to Human UMPS. Recombinant protein control fragment (Product #RP-96305).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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