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Invitrogen™ UMPS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116107

Catalog No. PIPA5116107


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Description

Description

Antibody detects endogenous levels of total UMPS.

This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

UMPS
Polyclonal
Unconjugated
UMPS
1700095D23Rik; AA408257; AL033308; BB164745; mutant uridine monophosphate synthase; ODC; OK/SW-cl.21; OMPdecase; OPRT; OPRTase; orotate phosphoribosyl transferase and orotidine-5'-decarboxylase; orotate phosphoribosyltransferase; Orotidine 5'-phosphate decarboxylase; UMP synthase; UMPS; Uridine 5'-monophosphate synthase; uridine 5-monophosphate synthase; uridine 5'-monophosphate synthase-like protein; uridine monophophate synthase; uridine monophosphate synthase; uridine monophosphate synthetase; uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase); uridine monophosphate synthetase [orotate phosphoribosyl transferase and orotidine-5'-decarboxylase]
Rabbit
Affinity chromatography
RUO
22247, 288051, 7372
-20°C
Liquid
Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide
P11172, P13439
UMPS
A synthesized peptide derived from human UMPS(Accession P11172), corresponding to amino acid residues R405-S455.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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