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Invitrogen™ UMPS Polyclonal Antibody
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Catalog No. PIPA543134
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100 μL
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PIPA543134 100 μL
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Catalog No. PIPA543134 Supplier Invitrogen™ Supplier No. PA543134
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Description

Rabbit Polyclonal Antibody

Peptide sequence: VGFISGSRVS MKPEFLHLTP GVQLEAGGDN LGQQYNSPQE VIGKRGSDII Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 93%; Yeast: 75%.

This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UMPS
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene UMPS
Gene Accession No. P11172
Gene Alias 1700095D23Rik; AA408257; AL033308; BB164745; mutant uridine monophosphate synthase; ODC; OK/SW-cl.21; OMPdecase; OPRT; OPRTase; orotate phosphoribosyl transferase and orotidine-5'-decarboxylase; orotate phosphoribosyltransferase; Orotidine 5'-phosphate decarboxylase; UMP synthase; UMPS; Uridine 5'-monophosphate synthase; uridine 5-monophosphate synthase; uridine 5'-monophosphate synthase-like protein; uridine monophophate synthase; uridine monophosphate synthase; uridine monophosphate synthetase; uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase); uridine monophosphate synthetase [orotate phosphoribosyl transferase and orotidine-5'-decarboxylase]
Gene Symbols UMPS
Host Species Rabbit
Immunogen Synthetic peptide directed towards the C-terminal of human UMPS (aa 398-447).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7372
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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