Invitrogen™ UMPS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA543134

Catalog No. PIPA543134

Description

Peptide sequence: VGFISGSRVS MKPEFLHLTP GVQLEAGGDN LGQQYNSPQE VIGKRGSDII Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 93%; Yeast: 75%.

This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Specifications

• Antigen: UMPS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UMPS
• Gene Alias: 1700095D23Rik; AA408257; AL033308; BB164745; mutant uridine monophosphate synthase; ODC; OK/SW-cl.21; OMPdecase; OPRT; OPRTase; orotate phosphoribosyl transferase and orotidine-5'-decarboxylase; orotate phosphoribosyltransferase; Orotidine 5'-phosphate decarboxylase; UMP synthase; UMPS; Uridine 5'-monophosphate synthase; uridine 5-monophosphate synthase; uridine 5'-monophosphate synthase-like protein; uridine monophophate synthase; uridine monophosphate synthase; uridine monophosphate synthetase; uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase); uridine monophosphate synthetase [orotate phosphoribosyl transferase and orotidine-5'-decarboxylase]
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7372
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P11172
• Gene Symbols: UMPS
• Immunogen: Synthetic peptide directed towards the C-terminal of human UMPS (aa 398-447).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG