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Tocris Bioscience™ UNC 0642
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Catalog No. 513210
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51-321-0 10 mg
51-325-0 50 mg
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Description

Potent and selective G9a and GLP inhibitor

UNC 0642 is a potent and selective G9a and GLP histone lysine methyltransferase inhibitor (IC50 < 2.5 nM) that exhibits >2,000-fold selectivity for G9a and GLP over PRC2-EZH2 and >20,000-fold selectivity over other methyltransferases. UNC 0642 reduces H3K9 dimethylation levels in MDA-MB-231 cells (IC50 = 110 nM), and displays modest brain penetration in vivo.

Specifications

Quantity 10 mg
Product Type UNC 0642
Purity >99%
Molecular Weight (g/mol) 546.7
Inhibitors UNC 0642

For Research Use Only

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