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Tocris Bioscience™ UNC 1999
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Catalog No. 490410
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Quantity:
10 mg
50 mg
Catalog No. Quantity
49-041-0 10 mg
49-045-0 50 mg
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Catalog No. 49-041-0

Supplier: Tocris Bioscience™ 4904/10

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Description

Potent and selective EZH2/EZH1 inhibitor

UNC 1999 is a potent and SAM-competitive EZH2/EZH1 lysine methyltransferase inhibitor (IC50 values are 10 and 45 nM, respectively). Selective for EZH2/EZH1 over a panel of other methyltransferases and non-epigenetic targets. Reduces H3K27me3 levels in vitro. Prolongs survival of MLL-AF9 bearing mice. Orally bioavailable.

Negative Control also available.

Specifications

Quantity 10 mg
Product Type UNC 1999
Purity >99%
Molecular Weight (g/mol) 569.74
Inhibitors UNC 1999

For Research Use Only

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