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Tocris Bioscience™ UNC 2881
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Catalog No. 653725
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25 mg
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65-372-5 25 mg
65-375 5 mg
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Catalog No. 65-372-5 Supplier Tocris Bioscience™ Supplier No. 6537/25
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Description

Potent Mer kinase inhibitor

UNC 2881 is a potent Mer kinase inhibitor. Displays >55-fold selectivity for Mer kinase over other TAM receptor tyrosine kinase family members (IC50 values are 4.3 nM, 0.25 μM and 0.36 μM for Mer, Tyro3 and Alk, respectively). Inhibits Mer phosphorylation in vitro. Also inhibits platelet aggregation in response to Type I collagen.

Specifications

Chemical Name or Material 2-(Butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-N-[[4-(1H-imidazol-1-yl)phenyl]methyl]-5-pyrimidinecarboxamide
CAS 1493764-08-1
Quantity 25 mg
Molecular Formula C25H33N7O2
Formula Weight 463.58
Purity 98%
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