Invitrogen™ UNC13B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555091

Catalog No. PIPA555091

Description

Immunogen sequence: SQLSELDQYH EQDDDHRETD SIHSCHSSHS LSRDGQAGFG EQEKPLEVTG QAEKEAACEP KEMKEDATTH PP Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 69%.

Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses.

Specifications

• Antigen: UNC13B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UNC13B
• Gene Alias: homolog of rat Munc13 (diacylglycerol-binding); munc13; Munc13-1; Munc13-2; protein unc-13 homolog B; UNC13; unc13 homolog 1; UNC-13 homolog 1; unc-13 homolog A; unc-13 homolog B; unc-13 homolog B (C. elegans); Unc13a; Unc13b; Unc13h1; Unc13h2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10497
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O14795
• Gene Symbols: UNC13B
• Immunogen: Recombinant protein corresponding to Human UNC13B. Recombinant protein control fragment (Product #RP-93102).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG