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Invitrogen™ UNC13B Polyclonal Antibody
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Catalog No. PIPA590699
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100 μL
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PIPA590699 100 μL
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Catalog No. PIPA590699 Supplier Invitrogen™ Supplier No. PA590699
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MSLLCVRVKR AKFQGSPDKF NTYVTLKVQN VKSTTVAVRG DQPSWEQDFM FEISRLDLGL SVEVWNKGLI WDTMVGTVWI ALKTIRQSDE EGPGEWSTLE AETLMKDDEI CGTRNPTPHK ILLDTRFELP FDIPEEEARY WTYKWEQINA LGADNEYSSQ EESQRKPLPT AAAQCSFEDP DSAVDDRDSD YRSETSNSFP PPYHTASQPN ASVHQFPVPV RSPQQLLLQG SSRDSCNDSM QSYDLDYPER RAISPTSSSR YGSSCNVSQG SSQLSELDQY HEQDDDHRET DSIHSCHSSH SLSRDGQAGF GEQEKPLEVT GQAEKEAACE PKEMKEDATT HPPPDLVLQK; Positive Samples: 293T, LO2; Cellular Location: Cell junction, Cell membrane, Cytoplasm, Membrane, Peripheral membrane protein, synapse.

Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UNC13B
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.46 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene UNC13B
Gene Accession No. O14795, Q9Z1N9
Gene Alias homolog of rat Munc13 (diacylglycerol-binding); munc13; Munc13-1; Munc13-2; protein unc-13 homolog B; UNC13; unc13 homolog 1; UNC-13 homolog 1; unc-13 homolog A; unc-13 homolog B; unc-13 homolog B (C. elegans); Unc13a; Unc13b; Unc13h1; Unc13h2
Gene Symbols UNC13B
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human UNC13B (NP_0063683).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10497, 22249
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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