Invitrogen™ UNC13B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522153

Catalog No. PIPA522153

Description

Recommended positive controls: 293T, H1299, HeLa, HepG2. Predicted reactivity: Mouse (99%), Rat (98%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses.

Specifications

• Antigen: UNC13B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UNC13B
• Gene Alias: homolog of rat Munc13 (diacylglycerol-binding); munc13; Munc13-1; Munc13-2; protein unc-13 homolog B; UNC13; unc13 homolog 1; UNC-13 homolog 1; unc-13 homolog A; unc-13 homolog B; unc-13 homolog B (C. elegans); Unc13a; Unc13b; Unc13h1; Unc13h2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10497, 64830
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O14795, Q62769
• Gene Symbols: UNC13B
• Immunogen: Recombinant fragment corresponding to a region within amino acids 680 and 957 of UNC13B (Uniprot ID#O14795).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG