UNC13D Monoclonal Antibody (OTI1F4), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA507267

Catalog No. 50-167-7039

Description

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

Specifications

• Antigen: UNC13D
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q70J99
• Gene Symbols: UNC13D
• Immunogen: Full length human recombit protein of human UNC13D produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1F4
• Conjugate: Unconjugated
• Gene: UNC13D
• Gene Alias: FHL3, HLH3, HPLH3, Munc13-4
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 201294
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid