Invitrogen™ Unc18-2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588599

Catalog No. PIPA588599

Description

Immunogen sequence: MAPSGLKAVV GEKILSGVIR SVKKDGEWKV LIMDHPSMRI LSSCCKMSDI LAEGITIVED INKRREPIPS LEAIYLLSPT EKALIKDFQG TPTFTYKAAH IFFTDTCPEP LFSELGRSRL AKVVKTLKEI HLAFLPYEAQ VFSLDAPHST YNLYCPFRAE ERTRQLEVLA QQIATLCATL QEYPAIRYRK GPEDTAQLAH AVLAKLNAFK ADTPSLGEGP EKTRSQLLIM DRAADPVSPL LHELTFQAMA YDLLDIEQDT YRYETTGLSE AREKAVLLDE; Positive Samples: THP-1, Jurkat, Mouse testis, Mouse thymus.

This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Specifications

• Antigen: Unc18-2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: STXBP2
• Gene Alias: C79054; FHL5; Hunc18b; Munc-18-2; Munc18-2; Munc18b; Munc-18b; muSec1; pp10122; Protein unc-18 homolog 2; protein unc-18 homolog B; Stxbp2; Sxtbp2; Sxtp2; syntaxin binding protein 2; syntaxin binding protein Munc18-2; syntaxin-binding protein 2; unc-18 homolog 2; unc-18 homolog B; Unc18-2; Unc18b; unc-18B
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20911, 6813
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.42 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q15833, Q64324
• Gene Symbols: STXBP2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human STXBP2 (NP_0011208681).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG