Invitrogen™ Unc18-2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521475

Catalog No. PIPA521475

Description

Recommended positive controls: HepG2, HCT116. Predicted reactivity: Mouse (95%), Rat (95%), Dog (93%), Chimpanzee (98%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Specifications

• Antigen: Unc18-2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: STXBP2
• Gene Alias: C79054; FHL5; Hunc18b; Munc-18-2; Munc18-2; Munc18b; Munc-18b; muSec1; pp10122; Protein unc-18 homolog 2; protein unc-18 homolog B; Stxbp2; Sxtbp2; Sxtp2; syntaxin binding protein 2; syntaxin binding protein Munc18-2; syntaxin-binding protein 2; unc-18 homolog 2; unc-18 homolog B; Unc18-2; Unc18b; unc-18B
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6813
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.51 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q15833
• Gene Symbols: STXBP2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human STXBP2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG