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Invitrogen™ UNC5CL Polyclonal Antibody
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Catalog No. PIPA530917
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100 μL
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PIPA530917 100 μL
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Catalog No. PIPA530917 Supplier Invitrogen™ Supplier No. PA530917
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Raji. Predicted reactivity: Human (99%), Mouse (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

UNC5CL is a membrane protein belonging to theUNC-5 family with a death domain and a ZU5 domain and is known to interact with p65/RELA and NFKB1. UNC5CL is known to interact with subunit p105 of NF-kappaB and transactivator p65 and is thus involved in inhibition of NF-kappaB activation and NF-kappaB-dependent transcription by inhibiting the binding of NF-kappaB to its target sequence (providing an alternative regulatory mechanism for NF-kappaB-mediated transcription). This regulatory protein sensitizes cells to apoptosis induced by TNF and TRAIL.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UNC5CL
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene UNC5CL
Gene Accession No. Q8IV45
Gene Alias 2510009H09Rik; BB155270; MGC34763; MUXA; OTTHUMP00000016362; protein unc-5 homolog C-like; unc-5 family C-terminal like; unc-5 homolog C (C. elegans)-like; UNC5CL; UNC5C-like protein; zu-5; ZU5 and death domain containing; ZU5 and death domain-containing inhibitor of NF-kB; ZU5 and death domain-containing protein; ZUD
Gene Symbols UNC5CL
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the Intracellular domain of human UNC5CL. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 222643
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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