Invitrogen™ UPB1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121510

Catalog No. PIPA5121510

Description

UPB1 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.

Specifications

• Antigen: UPB1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UPB1
• Gene Alias: AI195023; Beta-alanine synthase; beta-ureidopropionase; beta-ureidopropionase 1; BUP1; BUP-1; N-carbamoyl-beta-alanine amidohydrolase; UPB1; ureidopropionase, beta; wu:fb69e03; zgc:64020
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100155919, 116593, 51733
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: Q03248, Q9UBR1
• Gene Symbols: UPB1
• Immunogen: Recombinant protein Beta-ureidopropionase. The antigen corresponds to amino acid range 121-384 of the target protein.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Pig, Rat
• Product Type: Antibody
• Isotype: IgG