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UPF2 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA528629
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PIPA528629 100 μL
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Catalog No. PIPA528629 Supplier Thermo Scientific Supplier No. PA528629

Description

Rabbit Polyclonal Antibody

Recommended positive controls: mouse brain. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UPF2
Applications Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene UPF2
Gene Accession No. Q9HAU5
Gene Alias HUPF2; KIAA1408; Nonsense mRNA reducing factor 2; regulator of nonsense transcripts 2; RENT2; smg-3; smg-3 homolog, nonsense mediated mRNA decay factor; UPF2; UPF2 regulator of nonsense transcripts homolog (yeast); up-frameshift suppressor 2 homolog; yeast Upf2p homolog
Gene Symbols UPF2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to a region within amino acids 1200 and 1272 of Human Rent2
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26019, 326622
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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