Invitrogen™ Urocortin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104471

Catalog No. PIPA5104471

Description

Antibody detects endogenous levels of total Urocortin.

Urocortin (UCN), a 40 amino acids neuropeptide widely distributed in the central nervous system (CNS), belongs to a family of structurally related peptides including corticotrophin releasing factor (CRF), sauvagine and urotensin I. Urocortin is derived from a larger precursor protein (pro-urocortin, also named corticotensin). Urocortin has biological actions similar to CRF such as stress-related endocrine, autonomic and behavioral responses in mammalian species. It is a potent stimulator of adrenocorticotropic hormone (ACTH) secretion by corticotroph cells from the anterior pituitary in vitro and in vivo.

Specifications

• Antigen: Urocortin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ucn
• Gene Alias: Corticotensin; Mpv17; prepro-urocortin; Ucn; Ucn1; UI; UROC; Urocortin; urocortin, preproprotein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22226, 29151, 7349
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P55089, P55090, P81615
• Gene Symbols: Ucn
• Immunogen: A synthesized peptide derived from human UCN(Accession P55089), corresponding to amino acid residues L19-G69.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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