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Tocris Bioscience™ Urolithin A

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Quantity:
10 mg
50 mg
Description
Urolithin A is a PI 3-K/Akt/mTOR signaling pathway inhibitor; blocks phosphorylation of Akt and p70S6K in pancreatic ductal adenocarcinoma (PDAC). Inhibits proliferation and migration and promotes apoptosis of PDAC cell lines in vitro (IC50 values are 10.23 - 62.28 μM). Suppresses tumor growth and improves survival in mice bearing pancreatic tumor xenografts. Also blocks amyloid-β fibrillation in vitro.
Specifications
Specifications
Chemical Name or Material | 3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one |
CAS | 1143-70-0 |
Quantity | 10 mg |
Molecular Formula | C13H8O4 |
Formula Weight | 228.2 |
Purity | 98% |
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