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Invitrogen™ US12 Polyclonal Antibody
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Catalog No. FEPA5144429
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100 μL
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FEPA5144429 100 μL
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Catalog No. FEPA5144429 Supplier Invitrogen™ Supplier No. PA5144429
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Description

Rabbit Polyclonal Antibody

US12 Polyclonal Antibody for Western Blot, ELISA

Plays a role in the inhibition of host immune response. Binds specifically to transporters associated with antigen processing (TAP), thereby blocking peptide-binding and translocation by TAP as well as subsequent loading of peptides onto MHC class I molecules. Empty MHC I molecules are retained in the endoplasmic reticulum and ultimately directed to proteasomal degradation. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen US12
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.249 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
Gene US12
Gene Accession No. P03170
Gene Alias ICP47 protein; US12
Gene Symbols US12
Host Species Rabbit
Immunogen Recombinant Human herpesvirus 1 ICP47 protein (US12) (1-88aa).
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2703441
Target Species Virus
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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