Invitrogen™ US12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5144430

Catalog No. FEPA5144430

Description

US12 Polyclonal Antibody for Western Blot, ELISA

Plays a role in the inhibition of host immune response. Binds specifically to transporters associated with antigen processing (TAP), thereby blocking peptide-binding and translocation by TAP as well as subsequent loading of peptides onto MHC class I molecules. Empty MHC I molecules are retained in the endoplasmic reticulum and ultimately directed to proteasomal degradation. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes.

Specifications

• Antigen: US12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: US12
• Gene Alias: ICP47 protein; US12
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 2703441
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.263 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
• Gene Accession No.: P03170
• Gene Symbols: US12
• Immunogen: Recombinant Herpes simplex virus type 2 ICP47 protein (US12) (1-78aa).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG