Invitrogen™ USP10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596706

Catalog No. PIPA596706

Description

Immunogen sequence: FEPTYIYRLL TVNKSSLSEK GRQEDAEEYL GFILNGLHEE MLNLKKLLSP SNEKLTISNG PKNHSVNEEE QEEQGEGSED EWEQVGPRNK TSVTRQADFV QTPITGIFGG HIRSVVYQQS SKESATLQPF FTLQLDIQSD KIRTVQDALE SLVARESVQG YTTKTKQEVE ISRRVTLEKL PPVLVLHLKR FVYEKTGGCQ KLIKNIEYPV DLEISKELLS PGVKNKNFKC HRTYRLFAVV YHHGNSATGG HYTTDVFQIG LNGWLRIDDQ TVKVINQYQV VKPTAERTAY LLYYRRVDLL; Positive Samples: HepG2, Mouse brain; Cellular Location: Cytoplasm, Early endosome, Nucleus.

USP10, also known as ubiquitin specific peptidase 10, belongs to the ubiquitin-specific protease family of cysteine proteases. USP10 functions to catalyze the cleavage of ubiquitin from ubiquitin-conjugated protein substrates such as p53/TP53, SNX3 and CFTR. USP10 has been identified as a subunit of DNA-bound androgen receptor (AR) complexes and may play a role in the activity of the DNA-bound androgen receptor complex. USP10 also acts as an essential regulator of p53/TP53 stability and is thought to function as a tumor suppressor.

Specifications

• Antigen: USP10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Usp10
• Gene Alias: 2610014N07Rik; Deubiquitinating enzyme 10; KIAA0190; MGC2621; mKIAA0190; Ode-1; ubiquintin c-terminal hydrolase related polypeptide; ubiquitin carboxyl-terminal hydrolase 10; ubiquitin specific peptidase 10; ubiquitin specific protease 10; ubiquitin thioesterase 10; ubiquitin thiolesterase 10; ubiquitin-specific-processing protease 10; UBPO; Uchrp; USP10
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22224, 9100
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.12 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P52479, Q14694
• Gene Symbols: Usp10
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 499-798 of human USP10 (NP_0051442).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG