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Invitrogen™ USP11 Polyclonal Antibody
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Catalog No. PIPA527418
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100 μL
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Catalog No. Quantity
PIPA527418 100 μL
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Catalog No. PIPA527418 Supplier Invitrogen™ Supplier No. PA527418
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLaS3, IMR32. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

USP11 (ubiquitin specific peptidase 11), also known as UHX1, is a 920 amino acid deubiquitinating enzyme that participates in the Ub pathway. Localized to the nucleus, USP11 associates with both Ran BP-M (Ran binding protein M) and with the tumor suppressor BRCA2. Through these associations, USP11 functions to either inhibit ubiquitination of these proteins or to remove ubiquitin residues that have already been attached to these proteins. USP11 is implicated in several X-linked retinal diseases and, due to its ability to deubiquitinate BRCA2, may play a role in tumor suppression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen USP11
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene USP11
Gene Accession No. P51784
Gene Alias 6230415D12Rik; deubiquitinating enzyme 11; mKIAA4085; RP4-659F15.2; Ubiquitin carboxyl-terminal hydrolase 11; ubiquitin carboxyl-terminal hydrolase, X-linked; ubiquitin specific peptidase 11; ubiquitin specific protease 11; ubiquitin thioesterase 11; ubiquitin thiolesterase 11; ubiquitin-specific processing protease 11; ubiquitin-specific-processing protease 11; UHX1; USP11
Gene Symbols USP11
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human USP11. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8237
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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