Invitrogen™ USP11 Polyclonal Antibody

Catalog No.	Quantity
PIPA5101941	100 μL

Catalog No. PIPA5101941

Supplier: Invitrogen™ PA5101941

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total USP11.

USP11 (ubiquitin specific peptidase 11), also known as UHX1, is a 920 amino acid deubiquitinating enzyme that participates in the Ub pathway. Localized to the nucleus, USP11 associates with both Ran BP-M (Ran binding protein M) and with the tumor suppressor BRCA2. Through these associations, USP11 functions to either inhibit ubiquitination of these proteins or to remove ubiquitin residues that have already been attached to these proteins. USP11 is implicated in several X-linked retinal diseases and, due to its ability to deubiquitinate BRCA2, may play a role in tumor suppression.

Specifications

• Antigen: USP11
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: USP11
• Gene Accession No.: P51784, Q5D006, Q99K46
• Gene Alias: 6230415D12Rik; deubiquitinating enzyme 11; mKIAA4085; RP4-659F15.2; Ubiquitin carboxyl-terminal hydrolase 11; ubiquitin carboxyl-terminal hydrolase, X-linked; ubiquitin specific peptidase 11; ubiquitin specific protease 11; ubiquitin thioesterase 11; ubiquitin thiolesterase 11; ubiquitin-specific processing protease 11; ubiquitin-specific-processing protease 11; UHX1; USP11
• Gene Symbols: USP11
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human USP11(Accession P51784), corresponding to amino acid residues I221-L271.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 236733, 408217, 8237
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov