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Invitrogen™ USP11 Recombinant Rabbit Monoclonal Antibody (8I1K10)
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Catalog No. PIMA537919
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Quantity:
100 μL
Catalog No. Quantity
PIMA537919 100 μL
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Catalog No. PIMA537919

Supplier: Invitrogen™ MA537919

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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: HeLa, 293T, Jurkat, Mouse brain, Rat testis, Rat brain Immunogen sequence: WYCPSCKQHQ LATKKLDLWM LPEILIIHLK RFSYTKFSRE KLDTLVEFPI RDLDFSEFVI QPQNESNPEL YKYDLIAVSN HYGGMRDGHY TTFACNKDSG Q.

USP11 (ubiquitin specific peptidase 11), also known as UHX1, is a 920 amino acid deubiquitinating enzyme that participates in the Ub pathway. Localized to the nucleus, USP11 associates with both Ran BP-M (Ran binding protein M) and with the tumor suppressor BRCA2. Through these associations, USP11 functions to either inhibit ubiquitination of these proteins or to remove ubiquitin residues that have already been attached to these proteins. USP11 is implicated in several X-linked retinal diseases and, due to its ability to deubiquitinate BRCA2, may play a role in tumor suppression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen USP11
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 8I1K10
Concentration 2.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene USP11
Gene Accession No. P51784, Q5D006, Q99K46
Gene Alias 6230415D12Rik; deubiquitinating enzyme 11; mKIAA4085; RP4-659F15.2; Ubiquitin carboxyl-terminal hydrolase 11; ubiquitin carboxyl-terminal hydrolase, X-linked; ubiquitin specific peptidase 11; ubiquitin specific protease 11; ubiquitin thioesterase 11; ubiquitin thiolesterase 11; ubiquitin-specific processing protease 11; ubiquitin-specific-processing protease 11; UHX1; USP11
Gene Symbols USP11
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 800-900 of human USP11 (P51784).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 236733, 408217, 8237
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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