Invitrogen™ USP12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110554

Catalog No. PIPA5110554

Description

Immunogen sequence: MEILMTVSKF ASICTMGANA SALEKEIGPE QFPVNEHYFG LVNFGNTCYC NSVLQALYFC RPFREKVLAY KSQPRKKESL LTCLADLFHS IATQKKKVGV.

Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR20 and WDR48 to have a high activity (PubMed:19075014, PubMed:27373336). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014). In complex with WDR48, acts as a potential tumor suppressor by positively regulating PHLPP1 stability (PubMed:24145035). [UniProt].

Specifications

• Antigen: USP12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: USP12
• Gene Alias: Deubiquitinating enzyme 12; UBH1; Ubiquitin carboxyl-terminal hydrolase 12; ubiquitin hydrolyzing enzyme 1; ubiquitin specific peptidase 12; ubiquitin specific protease 12; ubiquitin specific protease 12 like 1; ubiquitin thioesterase 12; ubiquitin thiolesterase 12; ubiquitin-hydrolyzing enzyme 1; Ubiquitin-specific-processing protease 12; Usp12; USP12L1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 219333, 22217, 360763
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.79 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O75317, Q9D9M2
• Gene Symbols: USP12
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human USP12 (NP_8722942).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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