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USP19 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

$518.60

Specifications

Antigen USP19
Concentration 0.35 mg/mL
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-173-5065
SDP
Encompass_Preferred
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Proteintech Group Inc
257681AP150UL
150 μL
Each of 1 for $518.60
Only null left
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Description

Description

In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5′-region of the RUNX1 (AML1) gene fused to the 3′-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.
Specifications

Specifications

USP19
Immunoprecipitation, Western Blot
Unconjugated
Rabbit
Human
O94966
10869
USP19 Fusion Protein Ag22646
Primary
-20°C
USP19
0.35 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Deubiquitinating enzyme 19, KIAA0891, Ubiquitin thiolesterase 19, USP19, ZMYND9
USP19
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

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