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Invitrogen™ USP25 Monoclonal Antibody (1277CT376.106.171)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA537640

Catalog No. PIMA537640


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Description

Description

USP25 Monoclonal Antibody for Western Blot

Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

USP25
Monoclonal
0.49 mg/mL
PBS with 0.09% sodium azide; pH 7.4
Q9UHP3
Usp25
recombinant protein from human USP25.
400 μL
Primary
Human
Antibody
IgG1 κ
Western Blot
1277CT376.106.171
Unconjugated
Usp25
Deubiquitinating enzyme 25; mUSP25; Ubiquitin carboxyl-terminal hydrolase 25; ubiquitin specific peptidase 25; ubiquitin specific protease 25; ubiquitin thioesterase 25; ubiquitin thiolesterase 25; ubiquitin-specific processing protease 25; ubiquitin-specific-processing protease 25; USP on chromosome 21; USP21; Usp25
Mouse
Protein G
RUO
29761
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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