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Invitrogen™ USP34 Polyclonal Antibody
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Catalog No. PIPA5104200
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100 μL
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PIPA5104200 100 μL
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Catalog No. PIPA5104200 Supplier Invitrogen™ Supplier No. PA5104200
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total USP34.

Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen USP34
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene USP34
Gene Accession No. Q6ZQ93, Q70CQ2
Gene Alias A530081C03Rik; deubiquitinating enzyme 34; KIAA0570; KIAA0729; Murr2; U2af1-rs1 region 2; ubiquitin carboxyl-terminal hydrolase 34; ubiquitin specific peptidase 34; ubiquitin specific protease 34; ubiquitin thioesterase 34; ubiquitin thiolesterase 34; ubiquitin-specific-processing protease 34; Usp34
Gene Symbols USP34
Host Species Rabbit
Immunogen A synthesized peptide derived from human USP34(Accession Q70CQ2), corresponding to amino acid residues S516-D566.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17847, 9736
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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