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Invitrogen™ USP35 Polyclonal Antibody
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Catalog No. PIPA563086
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100 μL
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PIPA563086 100 μL
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Catalog No. PIPA563086 Supplier Invitrogen™ Supplier No. PA563086
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PPERCRRRRL GSVMRPTEDI TARELPPPTS AQGPGRVGPR RQRKHCITED TPPTSLYIEG LDSKEAGGQS SQEERIERE Highest antigen sequence identity to the following orthologs: Mouse - 53%, Rat - 58%.

p73 protein is a member of the p53 family of proteins. The tumor-suppressor protein p53 exhibits sequence specific DNA-binding, directly interacts with various cellular and viral proteins, and induces cell cycle arrest in response to DNA damage. In response to signals generated by a variety of genotoxic stresses, e.g, UV irradiation or DNA damage, p53 is expressed and undergoes post-translational modification that results in its accumulation in the nucleus. Activation of p53 leads to cell cycle arrest and in some cases to apoptosis, resulting in the inability of genetically damaged cells to proliferate. Thus, the p53-dependent pathways help to maintain genomic stability by eliminating damaged cells. The accumulation of high levels of p53 is a potential marker for malignancy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen USP35
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene USP35
Gene Accession No. Q9P2H5
Gene Alias Deubiquitinating enzyme 35; Gm1088; Gm493; KIAA1372; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 35; RGD1565984; Ubiquitin carboxyl-terminal hydrolase 35; ubiquitin specific peptidase 35; ubiquitin specific protease 35; ubiquitin thioesterase 35; ubiquitin thiolesterase 35; ubiquitin-specific-processing protease 35; USP34; USP35
Gene Symbols USP35
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human USP35. Recombinant protein control fragment (Product #RP-101228).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57558
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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