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Invitrogen™ USP35 Polyclonal Antibody
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Catalog No. PIPA5116110
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PIPA5116110 100 μL
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Catalog No. PIPA5116110 Supplier Invitrogen™ Supplier No. PA5116110
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total USP35.

p73 protein is a member of the p53 family of proteins. The tumor-suppressor protein p53 exhibits sequence specific DNA-binding, directly interacts with various cellular and viral proteins, and induces cell cycle arrest in response to DNA damage. In response to signals generated by a variety of genotoxic stresses, e.g, UV irradiation or DNA damage, p53 is expressed and undergoes post-translational modification that results in its accumulation in the nucleus. Activation of p53 leads to cell cycle arrest and in some cases to apoptosis, resulting in the inability of genetically damaged cells to proliferate. Thus, the p53-dependent pathways help to maintain genomic stability by eliminating damaged cells. The accumulation of high levels of p53 is a potential marker for malignancy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen USP35
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene USP35
Gene Accession No. Q9P2H5
Gene Alias Deubiquitinating enzyme 35; Gm1088; Gm493; KIAA1372; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 35; RGD1565984; Ubiquitin carboxyl-terminal hydrolase 35; ubiquitin specific peptidase 35; ubiquitin specific protease 35; ubiquitin thioesterase 35; ubiquitin thiolesterase 35; ubiquitin-specific-processing protease 35; USP34; USP35
Gene Symbols USP35
Host Species Rabbit
Immunogen A synthesized peptide derived from human USP35(Accession Q9P2H5), corresponding to amino acid residues S977-F1018.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57558
Target Species Human, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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