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Invitrogen™ USP5 Monoclonal Antibody (1340CT704.170.140)
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Catalog No. PIMA537650
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400 μL
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Catalog No. Quantity
PIMA537650 400 μL
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Catalog No. PIMA537650 Supplier Invitrogen™ Supplier No. MA537650
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Description

Mouse Monoclonal Antibody

USP5 Monoclonal Antibody for Western Blot

USP5 (ubiquitin carboxyl-terminal hydrolase 5) cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. It is involved in unanchored Lys-48-linked polyubiquitin disassembly, and also binds linear and Lys-63 linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
TRUSTED_SUSTAINABILITY

Specifications

Antigen USP5
Applications Western Blot
Classification Monoclonal
Clone 1340CT704.170.140
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene USP5
Gene Accession No. P45974, P56399
Gene Alias AA407472; deubiquitinating enzyme 5; EGK_03293; Isopeptidase T; Isot; ISOT-1; testicular tissue protein Li 218; ubiquitin carboxy terminal hydrolase T; ubiquitin carboxyl-terminal hydrolase 5; ubiquitin isopeptidase T; ubiquitin specific peptidase 5; ubiquitin specific peptidase 5 (isopeptidase T); ubiquitin specific protease 5; ubiquitin specific protease 5 (isopeptidase T); ubiquitin thioesterase 5; ubiquitin thiolesterase 5; ubiquitin-specific protease-5 (ubiquitin isopeptidase T); ubiquitin-specific-processing protease 5; Ucht; Usp5
Gene Symbols USP5
Host Species Mouse
Immunogen Recombinant protein from the human region of human USP5.
Purification Method Protein G
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22225, 297593, 8078
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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