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Invitrogen™ USP51 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA568358
Description
Predicted to react with Human, Mouse, and Rat samples.
USP51 (Ubiquitin Specific Peptidase 51) is a Protein Coding gene. Among its related pathways are Ubiquitin-Proteasome Dependent Proteolysis. Gene Ontology (GO) annotations related to this gene include cysteine-type endopeptidase activity and thiol-dependent ubiquitinyl hydrolase activity. Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'-linked di-ubiquitin.
Specifications
USP51 | |
Polyclonal | |
Unconjugated | |
USP51 | |
AV136873; Deubiquitinating enzyme 51; RGD1562211; Ubiquitin carboxyl-terminal hydrolase 51; ubiquitin specific peptidase 51; ubiquitin specific protease 51; ubiquitin thioesterase 51; ubiquitin thiolesterase 51; ubiquitin-specific-processing protease 51; Usp51 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
158880, 317398, 635253 | |
-20°C | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
Q70EK9 | |
USP51 | |
Synthesized peptide derived from human USP51. | |
100 μL | |
Primary | |
Human, Mouse, Rat, Monkey | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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