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Invitrogen™ USP51 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA568358

Catalog No. PIPA568358


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Description

Description

Predicted to react with Human, Mouse, and Rat samples.

USP51 (Ubiquitin Specific Peptidase 51) is a Protein Coding gene. Among its related pathways are Ubiquitin-Proteasome Dependent Proteolysis. Gene Ontology (GO) annotations related to this gene include cysteine-type endopeptidase activity and thiol-dependent ubiquitinyl hydrolase activity. Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'-linked di-ubiquitin.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

USP51
Polyclonal
Unconjugated
USP51
AV136873; Deubiquitinating enzyme 51; RGD1562211; Ubiquitin carboxyl-terminal hydrolase 51; ubiquitin specific peptidase 51; ubiquitin specific protease 51; ubiquitin thioesterase 51; ubiquitin thiolesterase 51; ubiquitin-specific-processing protease 51; Usp51
Rabbit
Affinity Chromatography
RUO
158880, 317398, 635253
-20°C
Liquid
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q70EK9
USP51
Synthesized peptide derived from human USP51.
100 μL
Primary
Human, Mouse, Rat, Monkey
Antibody
IgG
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