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Invitrogen™ USP6 Polyclonal Antibody
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Catalog No. PIPA544968
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100 μL
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PIPA544968 100 μL
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Catalog No. PIPA544968 Supplier Invitrogen™ Supplier No. PA544968
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Description

Rabbit Polyclonal Antibody

Peptide sequence: NHSEEDSTDD QREDTHIKPI YNLYAISCHS GILSGGHYIT YAKNPNCKWY Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 91%; Rat: 100%.

USP6 is a deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. It catalyzes its own deubiquitination. In vitro, isoform2, but not isoform3, shows deubiquitinating activity. USP6 promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. It is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen USP6
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene USP6
Gene Accession No. P35125
Gene Alias Deubiquitinating enzyme 6; HRP1; hyperpolymorphic gene 1; proto-oncogene TRE-2; TBC1D3 and USP32 fusion; TRE17; TRE2; Tre-2; TRESMCR; Ubiquitin carboxyl-terminal hydrolase 6; ubiquitin specific peptidase 6; ubiquitin specific peptidase 6 (Tre-2 oncogene); ubiquitin specific protease 6 (Tre-2 oncogene); ubiquitin thioesterase 6; ubiquitin thiolesterase 6; ubiquitin-specific protease USP6; ubiquitin-specific-processing protease 6; USP6; USP6-short
Gene Symbols USP6
Host Species Rabbit
Immunogen Synthetic peptide directed towards the C-terminal of human USP6 (aa 1292-1341).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9098
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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