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Invitrogen™ USP8 Monoclonal Antibody (460CT35.1.6)
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Catalog No. PIMA537573
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100 μL
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PIMA537573 100 μL
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Catalog No. PIMA537573 Supplier Invitrogen™ Supplier No. MA537573
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Mouse Monoclonal Antibody

USP8 Monoclonal Antibody for Western Blot

USP8 is a ubiquitin specific protease that plays an important regulatory role at the level of protein turnover by preventing degradation. USP8 is involved in cell proliferation, and probably regulates the stability of STAM2 and RASGRF1. USP8 may regulate T-cell energy mediated by RNF128 via the formation of a complex containing RNF128 and STAM2. As revealed by structure/function studies, USP8 forms a ternary complex with RNF128 and OTUB1, and interacts with the SH3 domain of STAM2 and RASGRF1. Expression of USP8 is induced Upon growth stimulation in starved human fibroblasts, and expression decreases in response to growth arrest induced by cell-cell contact.
TRUSTED_SUSTAINABILITY

Specifications

Antigen USP8
Applications Western Blot
Classification Monoclonal
Clone 460CT35.1.6
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.09% sodium azide; pH 7.4
Gene USP8
Gene Accession No. P40818
Gene Alias AI574262; AW557536; Deubiquitinating enzyme 8; hUBPy; HumORF8; Kiaa0055; mKIAA0055; mUBPy; putative deubiquitinating enzyme; SPG59; Ubiquitin carboxyl-terminal hydrolase 8; ubiquitin isopeptidase Y; ubiquitin specific peptidase 8; ubiquitin specific protease 8; ubiquitin thioesterase 8; ubiquitin thiolesterase 8; ubiquitin-specific-processing protease 8; Ubpy; USP8
Gene Symbols USP8
Host Species Mouse
Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the C-terminal region of human USP8.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9101
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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