USP8 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No.	Quantity
50-156-3840	10 μL

Catalog No. 50-156-3840 Supplier Bethyl Laboratories, Inc Supplier No. A302930AT

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

USP8 is a ubiquitin specific protease that plays an important regulatory role at the level of protein turnover by preventing degradation. USP8 is involved in cell proliferation, and probably regulates the stability of STAM2 and RASGRF1. USP8 may regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and STAM2. As revealed by structur/function studies, USP8 forms a ternary complex with RNF128 and OTUB1, and interacts with the SH3 domain of STAM2 and RASGRF1. Expression of USP8 is induced Upon growth stimulation in starved human fibroblasts, and expression decreases in response to growth arrest induced by cell-cell contact.

Specifications

• Antigen: USP8
• Applications: Immunoprecipitation
• Classification: Polyclonal
• Concentration: 1 mg/ml
• Conjugate: Unconjugated
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene: USP8
• Gene Accession No.: P40818
• Gene Alias: deubiquitinating enzyme 8, hUBPy, HumORF8, KIAA0055, SPG59, ubiquitin isopeptidase Y, ubiquitin specific protease 8, Ubiquitin thioesterase 8, ubiquitin thiolesterase 8, ubiquitin-specific-processing protease 8, UBPY
• Gene Symbols: USP8
• Host Species: Rabbit
• Immunogen: Between 1068 and 1118
• Purification Method: Antigen affinity chromatography
• Quantity: 10 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9101
• Target Species: Human
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG